This family presumably descends from John VI Cantacuzene, Byzantine Emperor ( 1347 - 1353 ). It is also known as Cantacuzene. Andronikos Cantacuzene was a wealthy Greek who supported Michael the Brave, Lord of Wallachia ( 1593 - 1600 ), in obtaining his throne. Of his four sons, Constantin, Gheorghe and Toma settled in the two Romanian Principalities, while Mihai remained in Constantinople and was the father of Dumitrașcu Cantacuzene, Lord of Moldavia ( 1674 - 1676; 1684 - 1685 ). Constantin was head of the Wallachian branch of the family and Gheorghe of the Moldavian one.
- Wallachian branch
- Moldavian branch